IDEAS home Printed from https://ideas.repec.org/a/wsi/srlxxx/v26y2019i09ns0218625x19500586.html
   My bibliography  Save this article

BIOCOMPATIBILITY STUDY OF α-Fe2O3 NANOPARTICLES PREPARED BY HYDROTHERMAL METHOD

Author

Listed:
  • SADEQ H. LAFTA

    (Applied Science Department, University of Technology, Iraq)

  • ALI ABDULRAHMAN TAHA

    (Applied Science Department, University of Technology, Iraq)

  • MUHAMMAD M. FARHAN

    (#x2020;Biotechnology Research Center, Al-Nahrain University, Iraq)

  • SHAIMA Y. ABDULFATTAH

    (#x2020;Biotechnology Research Center, Al-Nahrain University, Iraq)

Abstract

Nanoparticles of alpha ferric oxide (α-Fe2O3) were prepared by the hydrothermal method. Structural properties of α-Fe2O3 were determined by XRD, SEM and AFM measurements. The particles had a good matching with standard pattern. Average particle size was about 90nm and the distribution extended from about 20nm to 120nm. Biocompatibility study of ferric oxide nanoparticles against bacteria, parasites, tumor cell line and normal cells was determined. No antibacterial activity was observed for the concentration, of ferric oxide nanoparticles in distilled water, up to 1.5mg/ml vs. E. coli and S. aureus. Moreover, MTT assay was used to determine the cytotoxicity against parasites and cells. Intermediate cytotoxicity (53.30%) of 1.5mg/ml of prepared nanoparticles was noted against L. tropica, while weak cytotoxicity of 5.20% was observed against L. donovani at the same concentration of ferric oxide nanoparticles. On the other hand, the prepared nanoparticles revealed low cytotoxicity (47.28%) against SR tumor cell line, while no cytotoxicity was shown against lymphocytes, as a model of normal cells.

Suggested Citation

  • Sadeq H. Lafta & Ali Abdulrahman Taha & Muhammad M. Farhan & Shaima Y. Abdulfattah, 2019. "BIOCOMPATIBILITY STUDY OF α-Fe2O3 NANOPARTICLES PREPARED BY HYDROTHERMAL METHOD," Surface Review and Letters (SRL), World Scientific Publishing Co. Pte. Ltd., vol. 26(09), pages 1-8, November.
    • Handle: RePEc:wsi:srlxxx:v:26:y:2019:i:09:n:s0218625x19500586
    DOI: 10.1142/S0218625X19500586
    as

    Download full text from publisher

    File URL: http://www.worldscientific.com/doi/abs/10.1142/S0218625X19500586
    Download Restriction: Access to full text is restricted to subscribers
    File URL: https://libkey.io/10.1142/S0218625X19500586?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Keywords

    α-Fe2O3; biocompatibility; cytotoxicity; cancer; parasites; bacteria;
    All these keywords.

    JEL classification:

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:wsi:srlxxx:v:26:y:2019:i:09:n:s0218625x19500586. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Tai Tone Lim (email available below). General contact details of provider: http://www.worldscinet.com/srl/srl.shtml .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.