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Experimental Investigations On The Surface-Driven Capillary Flow Of Aqueous Microparticle Suspensions In The Microfluidic Laboratory-On-A-Chip Systems

Author

Listed:
  • SUBHADEEP MUKHOPADHYAY

    (Department of Electronics and Computer Engineering, National Institute of Technology, Arunachal Pradesh, India2Ministry of Human Resource Development (Government of India), Yupia, Papum Pare-791112, Arunachal Pradesh, India)

Abstract

In this work, total 1592 individual leakage-free polymethylmethacrylate (PMMA) microfluidic devices as laboratory-on-a-chip systems are fabricated by maskless lithography, hot embossing lithography, and direct bonding technique. Total 1094 individual Audio Video Interleave Files as experimental outputs related to the surface-driven capillary flow have been recorded and analyzed. The influence of effective viscosity, effect of surface wettability, effect of channel aspect ratio, and effect of centrifugal force on the surface-driven microfluidic flow of aqueous microparticle suspensions have been successfully and individually investigated in these laboratory-on-a-chip systems. Also, 5 micron polystyrene particles have been separated from the aqueous microparticle suspensions in the microfluidic lab-on-a-chip systems of modified design with 98% separation efficiency, and 10 micron polystyrene particles have been separated with 100% separation efficiency. About the novelty of this work, the experimental investigations have been performed on the surface-driven microfluidic flow of aqueous microparticle suspensions with the investigations on the separation time in particle-size based separation mechanism to control these suspensions in the microfluidic lab-on-a-chip systems. This research work contains a total of 10,112 individual experimental outputs obtained using total 30 individual instruments by author’s own hands-on completely during more than three years continuously. Author has performed the experimental investigations on both the fluid statics and fluid dynamics to develop an automated fluid machine.

Suggested Citation

  • Subhadeep Mukhopadhyay, 2017. "Experimental Investigations On The Surface-Driven Capillary Flow Of Aqueous Microparticle Suspensions In The Microfluidic Laboratory-On-A-Chip Systems," Surface Review and Letters (SRL), World Scientific Publishing Co. Pte. Ltd., vol. 24(08), pages 1-28, December.
    • Handle: RePEc:wsi:srlxxx:v:24:y:2017:i:08:n:s0218625x17501074
    DOI: 10.1142/S0218625X17501074
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