Functionalization Of Biomolecules With Nanostructured Porous Silicon For Biomedical Application

Porous silicon (PS) fabrication, changes in the optical properties and surface modification in the oxidized PS (dipped into the Glucose oxide) due to the infiltration of biomolecules using Luminescence Spectrophotometer [Photoluminescence (PL)], Fourier Transform Infrared Spectroscopy (FTIR), and Scanning Electron Microscope (SEM) were studied. The surface morphology of oxidized PS (OPS) and treated with Glucose have been studied by SEM. Spontaneous imbibition weight was calculated theoretically using imbibition equation for the porous medium using glucose solution as the wetting liquid. FTIR analysis revealed that, the strong Si–H, Si–O–Si bonds which covered most of the OPS surface. In the glucose treated PS layer, the amide I (C=O) stretch and amide II (C=N) stretch (1690 cm−1and 1551 cm−1) groups were appeared in the spectrum which confirmed the coupling reaction. Efficient visible Photoluminescence was obtained at around 624 nm from glucose treated porous silicon. The functionalization of glucose with nano structured PS, changes light emission over the surface of OPS. It can be applied in optical biosensor and which can be used in biomedical applications.