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Preparation Of Hydroxyapatite Coating On The Surface Of Hollow Glass Microspheres Using A Biomimetic Process

Author

Listed:
  • YAN JIAO

    (Shandong Institute of Commerce and Technology, Jinan 250103, China)

  • HAI-YING YANG

    (Shandong Institute of Commerce and Technology, Jinan 250103, China)

  • YING-LONG ZHANG

    (Shandong Institute of Commerce and Technology, Jinan 250103, China)

  • RONG-SHUAI DUAN

    (Shandong Institute of Commerce and Technology, Jinan 250103, China)

  • YU-PENG LU

    (School of Materials Science and Engineering, Shandong University, Jinan 250061, P. R. China)

Abstract

Microcarrier culture technology has attached more attention, especially for scale-up cell culture in the filed of tissue engineering. The present work introduces a microcarrier with hydroxyapatite (HA) on hollow glass microsphere. Hollow glass microspheres with a main composition ofSiO2(55–65 wt.%),Al2O3(26–35 wt.%), were pretreated byNaOH, on which hydroxyapatite coating was deposited by biomimetic process. The phase composition and morphology were characterized by X-ray diffractometer (XRD), Fourier transform infrared (FTIR) spectroscope, field emission scanning electron microscope (FE-SEM) and high resolution transmission electron microscope (HRTEM), respectively. The results showed that after immersion for 15 days in 1.5 SBF, the uniform and dense HA coating was formed and it has porous surface and low crystallinity.

Suggested Citation

  • Yan Jiao & Hai-Ying Yang & Ying-Long Zhang & Rong-Shuai Duan & Yu-Peng Lu, 2014. "Preparation Of Hydroxyapatite Coating On The Surface Of Hollow Glass Microspheres Using A Biomimetic Process," Surface Review and Letters (SRL), World Scientific Publishing Co. Pte. Ltd., vol. 21(05), pages 1-6.
    • Handle: RePEc:wsi:srlxxx:v:21:y:2014:i:05:n:s0218625x14500632
    DOI: 10.1142/S0218625X14500632
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