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Antimicrobial Resistance within Host: A Population Dynamics View

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  • Chunji Huang
  • Aijun Fan

Abstract

To study the relationship between antimicrobial resistance and the concentration of antibiotics, a competitive population dynamical model is proposed between the susceptible strain and the resistant strain with antibiotic exposure. The strict mathematical analysis is performed, and the results indicate that long‐term high strength antibiotic treatment and prevention can induce the extinction of susceptible strain. Thus, the prescribed dose of antibiotics must be strictly controlled during the treatment and prevention of the infections in clinics.

Suggested Citation

  • Chunji Huang & Aijun Fan, 2014. "Antimicrobial Resistance within Host: A Population Dynamics View," Abstract and Applied Analysis, John Wiley & Sons, vol. 2014(1).
    • Handle: RePEc:wly:jnlaaa:v:2014:y:2014:i:1:n:173952
    DOI: 10.1155/2014/173952
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    References listed on IDEAS

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    1. Kyle R. Allison & Mark P. Brynildsen & James J. Collins, 2011. "Metabolite-enabled eradication of bacterial persisters by aminoglycosides," Nature, Nature, vol. 473(7346), pages 216-220, May.
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