Optimizing Lumbar Spinal Fusion with Cellular Technologies

Degenerative-dystrophic diseases of the lumbar spine (DDSD) are a leading cause of temporary and permanentdisability, with significant advancements in surgical methods to address them. One crucial aspect of lumbar spinal fusionis the choice of bone grafting material, and the trend toward minimally invasive surgery has intensified the need for effectivealternatives to autologous bone. This research explores the potential of cellular technologies, specifically concentratedbone marrow aspirate (BMC), to enhance the outcomes of minimally invasive lumbar fusion for DDSD. The studyaims to comprehensively investigate the clinical and radiological results of spinal fusion using autologous bone, artificialbone substitutes, and BMC. It also involves the development of a technology for obtaining and utilizing BMC to augmentinterbody bone block formation. The findings provide insight into the effectiveness of cellular technologies in improvingthe success rates of spinal fusion and reducing specific negative radiological outcomes. This research is significant asit pioneers the use of BMC in enhancing minimally invasive interbody spinal fusion and offers practical implications forimproving patient outcomes in the treatment of DDSD.