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Prognostic Biomarkers in COVID-19: The Impact of Neutrophil-Lymphocyte Ratio, Ferritin, Platelet-Lymphocyte Ratio, and D-Dimer

Author

Listed:
  • Endang Sawitri

    (Laboratory of Physiology, Faculty of Medicine, Mulawarman University)

  • Lily Pertiwi Kalalo

    (Laboratory of Clinical Pathology, RSUD Abdoel Whab Sjahranie Samarida)

  • Muhammad Aidil Aulia Ramadhan

    (Medical Profession Study, Faculty of Medicine, Mulawarman University)

Abstract

Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, was declared a global pandemic by the World Health Organization (WHO) in March 2020. This indicates that identifying factors associated with mortality in affected patients is essential for optimizing clinical management. Therefore, this study aims to analyze the differences in Neutrophil-Lymphocyte Ratio (NLR), ferritin, Platelet-Lymphocyte Ratio (PLR), and D-dimer levels between COVID-19 patients who recovered and those who did not, as well as identify the key prognostic factors. The study was conducted using a cross-sectional method at RSUD Abdoel Wahab Sjahranie, Indonesia, from January to December 2021. The sample population consisted of adult COVID-19 patients with complete data on neutrophil, lymphocyte, and platelet counts, as well as ferritin and D-dimer levels. Among the 682 patients, the average age was 53.43 years, where 66.9% recovered and 33.1% died. The results showed that there were significant differences in NLR, ferritin, and D-dimer levels between the recovered and deceased groups (p

Suggested Citation

  • Endang Sawitri & Lily Pertiwi Kalalo & Muhammad Aidil Aulia Ramadhan, 2026. "Prognostic Biomarkers in COVID-19: The Impact of Neutrophil-Lymphocyte Ratio, Ferritin, Platelet-Lymphocyte Ratio, and D-Dimer," Technium BioChemMed: Journal of Multidisciplinary Research, Biology, Chemistry and Medicine ISSN 2734 - 7990, Technium Science, vol. 14, pages 17-23, April.
    • Handle: RePEc:tec:bioche:ojs:12620
    DOI: 10.47577/biochemmed.v14i.12620
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