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The Role of IgA and IgG anti-transglutaminase antibodies in the diagnosis of celiac disease in children

Author

Listed:
  • Lacramioara Ilie

    (Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania & City Hospital Targu Bujor, Galati, Romania)

  • Andreea Popa

    (Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania)

  • Larisa Gorofitei

    (Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania & Emergency Clinical Hospital for Children “Sf. Ioan” Galati, Romania)

  • Roxana Matache

    (Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania & Emergency Clinical Hospital for Children “Sf. Ioan” Galati, Romania)

  • Eliza Andreea Zaharia

    (Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania & Emergency Clinical Hospital for Children “Sf. Ioan” Galati, Romania)

  • Cristina Chelmu

    (Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania)

  • Lenuta Ambrose

    (Dunarea de Jos”University, Doctoral School of Biomedical Sciences of Galati, Romania)

  • Ionica Grigore

    (“Dunarea de Jos” University, Faculty of Medicine and Pharmacy Galati, Romania & Emergency County Hospital Braila, Romania)

  • Daniela Mihalache

    (“Dunarea de Jos” University, Faculty of Medicine and Pharmacy Galati, Romania & Emergency County Hospital Braila, Romania)

  • Gabriela Gurău

    (“Dunarea de Jos” University, Faculty of Medicine and Pharmacy Galati, Romania & Emergency Clinical Hospital for Children “Sf. Ioan” Galati, Romania)

  • Doina Carina Voinescu

    (“Dunarea de Jos” University, Faculty of Medicine and Pharmacy Galati, Romania & Emergency Clinical Hospital “Sf. Ap.Andrei ” Galati, Romania)

Abstract

Aims: Diagnosing celiac disease in children presents various challenges for pediatricians in the various clinical stages. Thus, the diagnosis of cases increased significantly, although children did not always present symptoms or clinical signs of the disease. In support of the diagnosis, several factors come into play: screening, serological tests, awareness of the presence of celiac disease and the factors that favor its occurrence. Material and methods: We performed a retrospective study at the Pediatric Clinical Hospital "St. Ioan " Galati between January 1, 2014 and October 2022. In this study we included 2640 children with suggestive symptoms of celiac disease. Results: A number of 102 patients were diagnosed with celiac disease, recurrent abdominal pain being the most common symptom.

Suggested Citation

  • Lacramioara Ilie & Andreea Popa & Larisa Gorofitei & Roxana Matache & Eliza Andreea Zaharia & Cristina Chelmu & Lenuta Ambrose & Ionica Grigore & Daniela Mihalache & Gabriela Gurău & Doina Carina Voin, 2023. "The Role of IgA and IgG anti-transglutaminase antibodies in the diagnosis of celiac disease in children," Technium BioChemMed: Journal of Multidisciplinary Research, Biology, Chemistry and Medicine ISSN 2734 - 7990, Technium Science, vol. 6, pages 56-59, December.
    • Handle: RePEc:tec:bioche:ojs:10297
    DOI: 10.47577/biochemmed.v6i.10297
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