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Mixture mean residual life model for competing risks data with mismeasured covariates

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  • Chyong-Mei Chen
  • Chih-Ching Lin
  • Chih-Cheng Wu
  • Jia-Ren Tsai

Abstract

This paper proposes a mixture regression model for competing risks data, where the logistic regression model is specified for the marginal probabilities of the failure types and the mean residual lifetime (MRL) model is assumed for the failure time given the failure of interest. The estimating equations (EEs) are derived to infer the logistic regression and MRL model separately. We further consider the situation where the covariates are subject to measurement error. The presence of measurement error imposes extra challenges for the analysis of complex time-to-event data. By using the above EEs as the correction-amenable original estimating functions, we propose a corrected score estimation, which does not require specifying the distributions for unobserved error-prone covariates. The proposed estimators are shown to be consistent and asymptotically normally distributed. The performance of the method is investigated by intensive simulation studies and two real examples are presented to illustrate the proposed methods.

Suggested Citation

  • Chyong-Mei Chen & Chih-Ching Lin & Chih-Cheng Wu & Jia-Ren Tsai, 2025. "Mixture mean residual life model for competing risks data with mismeasured covariates," Journal of Applied Statistics, Taylor & Francis Journals, vol. 52(7), pages 1361-1380, May.
  • Handle: RePEc:taf:japsta:v:52:y:2025:i:7:p:1361-1380
    DOI: 10.1080/02664763.2024.2426015
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