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Screening opportunity bias in case-control studies of cancer screening

Author

Listed:
  • Stephen Duffy
  • Anne-Helene Olsen
  • Rhian Gabe
  • Laszlo Tabar
  • Jane Warwick
  • Hilary Fielder
  • Laufey Tryggvadottir
  • Olorunsola Agbaje

Abstract

In case-control evaluations of cancer screening, subjects who have died from the cancer in question (cases) are compared with those who have not (controls) with respect to screening histories. This method is subject to a rather subtle bias, among others, whereby the cases have greater opportunity to have been screened than the controls. In this paper, we propose a method of correction for this bias. We demonstrate its use on two case-control studies of mammographic screening for breast cancer.

Suggested Citation

  • Stephen Duffy & Anne-Helene Olsen & Rhian Gabe & Laszlo Tabar & Jane Warwick & Hilary Fielder & Laufey Tryggvadottir & Olorunsola Agbaje, 2008. "Screening opportunity bias in case-control studies of cancer screening," Journal of Applied Statistics, Taylor & Francis Journals, vol. 35(5), pages 537-546.
    • Handle: RePEc:taf:japsta:v:35:y:2008:i:5:p:537-546
    DOI: 10.1080/02664760701835755
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