IDEAS home Printed from https://ideas.repec.org/a/taf/gcmbxx/v17y2014i8p875-887.html
   My bibliography  Save this article

Numerical simulation of the effect of permeability on the hydrodynamics in a parallel-plate coculture flow chamber

Author

Listed:
  • Ye Zeng
  • Xing-Hong Yao
  • Xiao-Heng Liu

Abstract

To study the effect of the porous membrane permeability on the hydrodynamics in a parallel-plate coculture flow chamber (PPcFC), we demonstrated the permeability of the porous membrane as a function of some parameters, such as porosity, membrane thickness, pore size and shape of the membrane. The effect of permeability on the flow in the PPcFC was analysed using the commercial software – Fluent. Results showed that the permeability was directly proportional to the thickness, the porosity and the pore size of the membrane, and inversely proportional to the surface shape factor. To ensure the best flow pattern, the inlet velocity range was limited by the membrane permeability and fluid viscosity, and then restricted the available magnitudes of shear rate on the permeable membrane. Our findings are helpful in designing and preparing the biomaterials that have adequate mechanical properties for the functional vascular grafts production, and in using of the flow chamber in various investigations.

Suggested Citation

  • Ye Zeng & Xing-Hong Yao & Xiao-Heng Liu, 2014. "Numerical simulation of the effect of permeability on the hydrodynamics in a parallel-plate coculture flow chamber," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 17(8), pages 875-887, June.
    • Handle: RePEc:taf:gcmbxx:v:17:y:2014:i:8:p:875-887
    DOI: 10.1080/10255842.2012.723699
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.1080/10255842.2012.723699
    Download Restriction: Access to full text is restricted to subscribers.
    File URL: https://libkey.io/10.1080/10255842.2012.723699?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:taf:gcmbxx:v:17:y:2014:i:8:p:875-887. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Chris Longhurst (email available below). General contact details of provider: http://www.tandfonline.com/gcmb .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.