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Importance of realistic LVAD profiles for assisted aortic simulations: evaluation of optimal outflow anastomosis locations

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  • Alistair Brown
  • Yubing Shi
  • Andreas Arndt
  • Jörg Müller
  • Patricia Lawford
  • David Hose

Abstract

Left ventricular assist devices (LVADs) are carefully designed, but the significance of the implantation configuration and interaction with the vasculature is complex and not fully determined. The present study employs computational fluid dynamics to investigate the importance of applying a realistic LVAD profile when evaluating assisted aortic flow fields and subsequently compares a number of potential anastomosis locations in a patient-specific aortic geometry. The outflow profile of the Berlin Heart INCOR® device was provided by Berlin Heart GmbH (Berlin, Germany) and the cannula was attached at a number of locations on the aorta. Simulations were conducted to compare a flat profile against the real LVAD profile. The results illustrate the importance of applying an LVAD profile. It not only affects the magnitude and distribution of oscillatory shear index, but also the distribution of flow to the great arteries. The ascending aorta was identified as the optimal location for the anastomosis.

Suggested Citation

  • Alistair Brown & Yubing Shi & Andreas Arndt & Jörg Müller & Patricia Lawford & David Hose, 2012. "Importance of realistic LVAD profiles for assisted aortic simulations: evaluation of optimal outflow anastomosis locations," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 15(6), pages 669-680.
    • Handle: RePEc:taf:gcmbxx:v:15:y:2012:i:6:p:669-680
    DOI: 10.1080/10255842.2011.556628
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    1. Alberto Marzo & Pankaj Singh & Philippe Reymond & Nikos Stergiopulos & Umang Patel & Rodney Hose, 2009. "Influence of inlet boundary conditions on the local haemodynamics of intracranial aneurysms," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 12(4), pages 431-444.
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