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Identification of heterogeneous elastic properties in stenosed arteries: a numerical plane strain study

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  • Alexandre Franquet
  • Stéphane Avril
  • Rodolphe Le Riche
  • Pierre Badel

Abstract

Assessing the vulnerability of atherosclerotic plaques requires an accurate knowledge of the mechanical properties of the plaque constituents. It is possible to measure displacements in vivo inside a plaque using magnetic resonance imaging. An important issue is to solve the inverse problem that consists in estimating the elastic properties inside the plaque from measured displacements. This study focuses on the identifiability of elastic parameters, e.g. on the compromise between identification time and identification accuracy. An idealised plane strain finite element (FE) model is used. The effects of the FE mesh of the a priori assumptions about the constituents, of the measurement resolution and of the data noise are numerically investigated.

Suggested Citation

  • Alexandre Franquet & Stéphane Avril & Rodolphe Le Riche & Pierre Badel, 2012. "Identification of heterogeneous elastic properties in stenosed arteries: a numerical plane strain study," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 15(1), pages 49-58.
    • Handle: RePEc:taf:gcmbxx:v:15:y:2012:i:1:p:49-58
    DOI: 10.1080/10255842.2010.547192
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    Cited by:

    1. Ali C. Akyildiz & Lambert Speelman & Harm A. Nieuwstadt & Harald van Brummelen & Renu Virmani & Aad van der Lugt & Anton F.W. van der Steen & Jolanda J. Wentzel & Frank J.H. Gijsen, 2016. "The effects of plaque morphology and material properties on peak cap stress in human coronary arteries," Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis Journals, vol. 19(7), pages 771-779, May.

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