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The Effect of Chromium and Boron on the Lipid Peroxidation and Antioxidant Status in Experiment

Author

Listed:
  • Marat IZTLEUOV

    (Department of Natural Science Disciplines West Kazakhstan Marat Ospanov State Medical University Aktobe Kazakhstan)

  • Zhanat UMIRZAKOVA

    (Department of Natural Science Disciplines West Kazakhstan Marat Ospanov State Medical University Aktobe Kazakhstan)

  • Erbolat IZTLEUOV

    (Department of Internship West Kazakhstan Marat Ospanov State Medical University Aktobe Kazakhstan)

  • Sanimgul SAMBAEVA

    (Department of Natural Science Disciplines West Kazakhstan Marat Ospanov State Medical University Aktobe Kazakhstan)

  • Gulmira IZTLEUOVA

    (Department of Physiatry and Dermatology West Kazakhstan Marat Ospanov State Medical University Aktobe Kazakhstan)

  • Dariga YESMUKHANOVA

    (Department of Natural Science Disciplines West Kazakhstan Marat Ospanov State Medical University Aktobe Kazakhstan)

  • Ainur AKHMETOVA

    (Department of Natural Science Disciplines West Kazakhstan Marat Ospanov State Medical University Aktobe Kazakhstan)

  • Raushan MEDEUOVA

    (Department of Natural Science Disciplines West Kazakhstan Marat Ospanov State Medical University Aktobe Kazakhstan)

  • Indira KOLISHBAEVA

    (Department of Natural Science Disciplines West Kazakhstan Marat Ospanov State Medical University Aktobe Kazakhstan)

Abstract

Current anthropogenic factors have a destructive effect on the environment In this connection it becomes necessary to study the negative effects of substances on living organisms and ways to reduce them This article evaluated the impact of potassium dichromate K2Cr2O7 and boric acid H3BO3 on the status of lipid peroxidation LPO and antioxidant system The work is performed on 24 male rats of Wistar weighing 180 220 g were grown in the vivarium of the Central research laboratory of West Kazakhstan state medical University named after Ospanov An experiment on Wistar rats 1st warning 2nd received K2Cr2O7 3rd H3BO3 4th K2Cr2O7 and H3BO The introduction of K2Cr2O7 intensified LPO and reduced activity of catalase glutathione peroxidase and superoxide dismutase the number of sulfhydryl groups The results of the study allow asserting that the H3BO3 in the conditions of joint use with K2Cr2O7 has an antioxidant effect which leads to inhibition of LPO and activation of antioxidant system Therefore we first established the antioxidant effect of boric acid in the combined effects of potassium dichromate and boric acid

Suggested Citation

  • Marat IZTLEUOV & Zhanat UMIRZAKOVA & Erbolat IZTLEUOV & Sanimgul SAMBAEVA & Gulmira IZTLEUOVA & Dariga YESMUKHANOVA & Ainur AKHMETOVA & Raushan MEDEUOVA & Indira KOLISHBAEVA, 2017. "The Effect of Chromium and Boron on the Lipid Peroxidation and Antioxidant Status in Experiment," Journal of Advanced Research in Management, ASERS Publishing, vol. 8(3), pages 529-536.
    • Handle: RePEc:srs:jemt00:v:8:y:2017:i:3:p:529-536
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