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Psychometric Validation of the Growth Hormone Deficiency–Child Treatment Burden Measure (GHD-CTB) and the Growth Hormone Deficiency–Parent Treatment Burden Measure (GHD-PTB)

Author

Listed:
  • Meryl Brod

    (The Brod Group)

  • Michael Højby Rasmussen

    (Novo Nordisk A/S)

  • Suzanne Alolga

    (The Brod Group)

  • Jane F. Beck

    (The Brod Group)

  • Donald M. Bushnell

    (Evidera | PPD)

  • Kai Wai Lee

    (Novo Nordisk A/S
    AstraZeneca)

  • Aristides Maniatis

    (Rocky Mountain Pediatric Endocrinology)

Abstract

Purpose The aim was to evaluate the measurement properties of the Growth Hormone Deficiency–Child Treatment Burden Measure–Child (GHD-CTB–Child), a patient-reported outcome (PRO) for children aged 9 to 0.70). Test–retest reliability was acceptable for the Physical, Emotional, and Overall domains of the GHD-CTB versions, and the Emotional and Overall domains of the GHD-PTB (intraclass correlation coefficient above 0.70). All but one of the convergent validity hypotheses for the GHD-CTB versions and all hypotheses for the GHD-PTB were proven (r > 0.40). Known-groups validity hypotheses were significant for length of time to administer the injections in the GHD-CTB versions (p

Suggested Citation

  • Meryl Brod & Michael Højby Rasmussen & Suzanne Alolga & Jane F. Beck & Donald M. Bushnell & Kai Wai Lee & Aristides Maniatis, 2023. "Psychometric Validation of the Growth Hormone Deficiency–Child Treatment Burden Measure (GHD-CTB) and the Growth Hormone Deficiency–Parent Treatment Burden Measure (GHD-PTB)," PharmacoEconomics - Open, Springer, vol. 7(1), pages 121-138, January.
    • Handle: RePEc:spr:pharmo:v:7:y:2023:i:1:d:10.1007_s41669-022-00373-z
    DOI: 10.1007/s41669-022-00373-z
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