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The Burden of Disease in Rheumatoid Arthritis

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  • Till Uhlig
  • Rikke Moe
  • Tore Kvien

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease which, if left untreated, leads to functional disability, pain, reduced health-related quality of life and premature mortality. Between 0.5 % and 1 % of the population are affected worldwide, and between 25 and 50 new cases evolve in a population of 100,000. Practically all patients with RA require initiation with disease-modifying antirheumatic treatment to retard or stop progression, control disease manifestations and reduce the disease burden. If disease course is monitored with adjustment of medication, lifestyle factors, and exercise, as well as physical activity levels, co-morbidities may be prevented in the course of RA. During the last decade, major progress has been made in treating RA through early identification and treatment of the disease. Many patients still experience premature work disability and co-morbidities. For societies, the economic burden of RA is high in terms of direct and indirect costs, including modern drug treatment. Copyright Springer International Publishing Switzerland 2014

Suggested Citation

  • Till Uhlig & Rikke Moe & Tore Kvien, 2014. "The Burden of Disease in Rheumatoid Arthritis," PharmacoEconomics, Springer, vol. 32(9), pages 841-851, September.
  • Handle: RePEc:spr:pharme:v:32:y:2014:i:9:p:841-851
    DOI: 10.1007/s40273-014-0174-6
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    Cited by:

    1. Massimo Radin & Marta Arbrile & Irene Cecchi & Pierluigi Di Nunzio & Nicola Buccarano & Federico Di Gregorio & Valeria Milone & Sara Osella & Paola Crosasso & Marika Denise Favuzzi & Alice Barinotti &, 2022. "Tailoring Tofacitinib Oral Therapy in Rheumatoid Arthritis: The TuTOR App," IJERPH, MDPI, vol. 19(9), pages 1-11, April.
    2. Xavier Janssens & Saskia Decuman & Filip De Keyser & Belgian Rheumatoid Arthritis Disability Assessment study group, 2016. "Comparison of the Belgian Rheumatoid Arthritis Disability Assessment and Health Assessment Questionnaires as Tools to Predict the Need for Support Measures in Patients with Rheumatoid Arthritis," PLOS ONE, Public Library of Science, vol. 11(1), pages 1-11, January.
    3. Monika Laugesen & Mette Rasmussen & Robin Christensen & Hanne Tønnesen & Henning Bliddal, 2022. "Smoking Cessation Rates among Patients with Rheumatoid Arthritis and Osteoarthritis Following the ‘Gold Standard Programme’ (GSP): A Prospective Analysis from the Danish Smoking Cessation Database," IJERPH, MDPI, vol. 19(10), pages 1-14, May.

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