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Psychometric benefits of adding bolt-ons to the EQ-5D-5L in populations undergoing minimally invasive cosmetic procedures

Author

Listed:
  • Eszter Mercédesz Müller

    (Semmelweis University)

  • Anna Nikl

    (Semmelweis University Doctoral School
    Corvinus University of Budapest)

  • Máté Krebs

    (Semmelweis University)

  • Péter Holló

    (Semmelweis University)

  • Valentin Brodszky

    (Corvinus University of Budapest)

  • Lajos Vince Kemény

    (Semmelweis University
    Semmelweis University
    Semmelweis University)

  • Fanni Rencz

    (Semmelweis University Doctoral School
    Corvinus University of Budapest)

Abstract

Objectives There is growing interest in measuring health outcomes associated with minimally invasive cosmetic procedures (MICPs), such as botulinum toxin and hyaluronic acid injections. However, the EQ-5D may have limited content validity for this purpose. This study aims to psychometrically test five additional dimensions (‘bolt-ons’) for the EQ-5D-5L in individuals planning or undergoing MICPs. Methods In 2023, a cross-sectional, online survey was conducted with 149 women planning MICPs and 215 who had recently undergone them. Respondents completed the EQ-5D-5L, five bolt-ons (skin irritation, self-confidence, sleep, social relationships, tiredness), the Rosenberg Self-Esteem Scale (RSES) and the Brief Fear of Negative Evaluation Scale-Straightforward Items (BFNE-S). The following psychometric properties were tested for the EQ-5D-5L + bolt-on(s): ceiling, convergent and divergent validity, explanatory power and known-groups validity. Results Adding tiredness (22%), self-confidence (23%) or sleep bolt-ons (27%) substantially reduced the ceiling of the EQ-5D-5L (47%). The self-confidence and social relationships bolt-ons showed a moderate or strong correlation with the RSES and BFNE-S total scores (-0.462 to -0.679). The tiredness and self-confidence bolt-ons improved the EQ-5D-5L’s explained variance in EQ VAS scores from 37% to 45%. The self-confidence and social relationships bolt-ons improved the EQ-5D-5L’s discrimination between known groups based on self-esteem and bodily appearance (relative efficiency: 2.72 to 2.82). Conclusions Relevant bolt-ons substantially enhance the psychometric performance of the EQ-5D-5L in MICP populations. The self-confidence and tiredness bolt-ons may be recommended as primary choices for use alongside the EQ-5D-5L, both in clinical studies and as part of sensitivity analyses in economic evaluations of MICPs.

Suggested Citation

  • Eszter Mercédesz Müller & Anna Nikl & Máté Krebs & Péter Holló & Valentin Brodszky & Lajos Vince Kemény & Fanni Rencz, 2025. "Psychometric benefits of adding bolt-ons to the EQ-5D-5L in populations undergoing minimally invasive cosmetic procedures," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 26(7), pages 1233-1247, September.
  • Handle: RePEc:spr:eujhec:v:26:y:2025:i:7:d:10.1007_s10198-025-01772-9
    DOI: 10.1007/s10198-025-01772-9
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    References listed on IDEAS

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    1. Koonal Kirit Shah & Brendan Mulhern & Louise Longworth & M. F. Janssen, 2017. "Views of the UK General Public on Important Aspects of Health Not Captured by EQ-5D," The Patient: Patient-Centered Outcomes Research, Springer;International Academy of Health Preference Research, vol. 10(6), pages 701-709, December.
    2. Aureliano Paolo Finch & John Brazier & Clara Mukuria, 2021. "Selecting Bolt-on Dimensions for the EQ-5D: Testing the Impact of Hearing, Sleep, Cognition, Energy, and Relationships on Preferences Using Pairwise Choices," Medical Decision Making, , vol. 41(1), pages 89-99, January.
    3. N. Hamilton & C. Nelson & N. Stevens & Heather Kitzman, 2007. "Sleep and psychological well-being," Social Indicators Research: An International and Interdisciplinary Journal for Quality-of-Life Measurement, Springer, vol. 82(1), pages 147-163, May.
    4. Matthew Kennedy-Martin & Bernhard Slaap & Michael Herdman & Mandy Reenen & Tessa Kennedy-Martin & Wolfgang Greiner & Jan Busschbach & Kristina S. Boye, 2020. "Which multi-attribute utility instruments are recommended for use in cost-utility analysis? A review of national health technology assessment (HTA) guidelines," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 21(8), pages 1245-1257, November.
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