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Prescriber Variation in Relation to Prescribing Trends within the Preferred Drugs Initiative in Ireland (2012–2015): An Interrupted Time-Series Study Using Latent Curve Models

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  • Ronald D. McDowell

    (Health Research Board (HRB) Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland Medical School, Dublin 2, Ireland
    Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK)

  • Kathleen Bennett

    (Division of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland)

  • Frank Moriarty

    (Health Research Board (HRB) Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland Medical School, Dublin 2, Ireland)

  • Sarah Clarke

    (Health Service Executive Medicines Management Programme, Trinity Centre for Health Sciences, St. James’s Hospital, Dublin 8, Ireland)

  • Michael Barry

    (National Centre for Pharmacoeconomics, Trinity Centre for Health Sciences, St. James’s Hospital, Dublin 8, Ireland)

  • Tom Fahey

    (Health Research Board (HRB) Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland Medical School, Dublin 2, Ireland)

Abstract

Objectives. To examine the impact of the Preferred Drugs Initiative (PDI), an Irish health policy aimed at reducing prescribing variation. Design. Interrupted time series spanning 2012 to 2015. Setting. Health Service Executive pharmacy claims data for General Medical Services (GMS) patients, approximately 40% of the Irish population. Participants. Prescribers issuing preferred drug group items to GMS adults before and after PDI guidelines. Primary Outcome. The percentage coverage of PDI medications within each drug class per calendar quarter per prescriber. Methods. Latent curve models with structured residuals (LCM-SRs) were used to model coverage of the preferred drugs over time. The number of GMS adults receiving medication and the percentage who were 65 years and older at the start of the study were included as covariates. Results. In the quarter following PDI guidelines, coverage of the preferred drugs increased most in absolute terms for proton pump inhibitors (PPIs) (1.50% [SE 0.15], P

Suggested Citation

  • Ronald D. McDowell & Kathleen Bennett & Frank Moriarty & Sarah Clarke & Michael Barry & Tom Fahey, 2019. "Prescriber Variation in Relation to Prescribing Trends within the Preferred Drugs Initiative in Ireland (2012–2015): An Interrupted Time-Series Study Using Latent Curve Models," Medical Decision Making, , vol. 39(3), pages 278-293, April.
    • Handle: RePEc:sae:medema:v:39:y:2019:i:3:p:278-293
    DOI: 10.1177/0272989X18818165
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    References listed on IDEAS

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    1. Maria Ferrao Barbosa & Harvey Goldstein, 2000. "Discrete Response Multilevel Models for Repeated Measures: An Application to Voting Intentions Data," Quality & Quantity: International Journal of Methodology, Springer, vol. 34(3), pages 323-330, August.
    2. A. ConwayLenihan & S. Ahern & S. Moore & J. Cronin & N. Woods, 2016. "Factors influencing the variation in GMS prescribing expenditure in Ireland," Health Economics Review, Springer, vol. 6(1), pages 1-8, December.
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