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Exploration of Adherence to the Immunosuppressive Medication in Kidney Transplant Recipients Based on Theory of Planned Behavior

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  • Luo Yang
  • Hong-xia Liu
  • Yue Hu
  • Bei Zhang
  • Fu-cong Peng
  • Chang-yun Wei
  • Rui-ting Wang

Abstract

To investigate adherence to immunosuppressive medication (IM) in kidney transplant recipients (KTRs) and analyze the associated factors using the Theory of Planned Behavior (TPB). Data were collected at Time1 (T1) and 3 months later (T2). T1: the elements of the TPB, past behavior, beliefs about medicines, perceived social support were measured. T2: IM adherence was measured. Structural equation modeling was applied to analyze the associated factors of medication adherence. A total of 246 KTRs were included. The average IM adherence score of KTRs’ was 4.86 ( SD  = 1.63). Of the recipients, 39.43% had one aspect of non-adherence to IM. The model could explain 28.7% of the variance in adherence to IM ( R 2  = .287, p  = .006). TPB is a useful tool for understanding adherence to IM in KTRs. Caregivers can provide effective interventions during follow-up, which should focus on improving medication beliefs as well as provision of other external support especially from outside.

Suggested Citation

  • Luo Yang & Hong-xia Liu & Yue Hu & Bei Zhang & Fu-cong Peng & Chang-yun Wei & Rui-ting Wang, 2022. "Exploration of Adherence to the Immunosuppressive Medication in Kidney Transplant Recipients Based on Theory of Planned Behavior," Clinical Nursing Research, , vol. 31(6), pages 1189-1198, July.
    • Handle: RePEc:sae:clnure:v:31:y:2022:i:6:p:1189-1198
    DOI: 10.1177/10547738221096550
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    1. Okki Dhona Laksmita & Min-Huey Chung & Yuan-Mei Liao & Pi-Chen Chang, 2020. "Multidimensional Scale of Perceived Social Support in Indonesian adolescent disaster survivors: A psychometric evaluation," PLOS ONE, Public Library of Science, vol. 15(3), pages 1-12, March.
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