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Intrasubject Medication Adherence Patterns

Author

Listed:
  • Cynthia L. Russell

    (University of Missouri-Columbia)

  • Vicki S. Conn

    (University of Missouri-Columbia)

  • Catherine Ashbaugh

    (University of Missouri-Columbia)

  • Richard Madsen

    (University of Missouri-Columbia)

  • Karen Hayes

    (Wichita State University)

  • Gilbert Ross Jr

    (University of Missouri-Columbia)

Abstract

The purpose of this prospective descriptive study was to explore the patterns of intrasubject (between medication) adherence of two similarly timed, twice-daily medications using the Medication Event Management System ® electronic monitoring cap. Medication adherence was measured for 6 months using electronic monitoring in 25 adult renal-transplant recipients. Data were available from 7,119 electronic medication events. Results indicated that two twice-daily medications scheduled to be taken simultaneously were taken within 5 min of each other 77% of the time and within 10 min, 92% of the time. When only the first scheduled dose of the day was examined, the results are 79% and 95%, respectively. These findings are important to researchers and clinicians who must evaluate medication adherence in transplant recipients while balancing cost and subject burden. This study provides empirical support for monitoring a single immunosuppressive medication electronically to estimate medication adherence with double or triple immunosuppressive drug therapy.

Suggested Citation

  • Cynthia L. Russell & Vicki S. Conn & Catherine Ashbaugh & Richard Madsen & Karen Hayes & Gilbert Ross Jr, 2007. "Intrasubject Medication Adherence Patterns," Clinical Nursing Research, , vol. 16(2), pages 153-163, May.
    • Handle: RePEc:sae:clnure:v:16:y:2007:i:2:p:153-163
    DOI: 10.1177/1054773806296429
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