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Association between sexual dysfunction and symptom burden in women with Chronic Obstructive Pulmonary Disease

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  • Müfide Arzu Özkarafakılı
  • Cemil Kutsal
  • Nihat Türkmen
  • Hatice Yılmaz

Abstract

Objectives: To investigate sexual dysfunction as a clinically relevant but under-recognized manifestation of disease burden in women with COPD and to identify its clinical and psychological determinants. Study design: In this cross-sectional study, 100 consecutive women with stable COPD (mean age 57 ± 7 years) attending an outpatient chest clinic were enrolled. Main outcome measures: Participants underwent pulmonary function testing and completed the COPD Assessment Test (CAT), Modified Medical Research Council (mMRC) scale, Beck Depression Inventory, Short Form-36 (SF-36), Functional Assessment of Chronic Illness Therapy–Fatigue (FACIT-FS), and Female Sexual Function Index (FSFI). Results: Sexual dysfunction (FSFI ≤26.55) was more prevalent in patients with greater disease burden, particularly those in GOLD stage E, and was associated with significantly higher fatigue and depressive symptoms. FSFI scores showed a positive correlation with FACIT-FS and quality-of-life domains, and a negative correlation with depression scores (all p

Suggested Citation

  • Müfide Arzu Özkarafakılı & Cemil Kutsal & Nihat Türkmen & Hatice Yılmaz, 2026. "Association between sexual dysfunction and symptom burden in women with Chronic Obstructive Pulmonary Disease," PLOS ONE, Public Library of Science, vol. 21(9), pages 1-14, September.
    • Handle: RePEc:plo:pone00:0357921
    DOI: 10.1371/journal.pone.0357921
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