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Dementia as a risk factor for 30-day mortality in community-acquired pneumonia in Colombia (CAP): A survival study

Author

Listed:
  • Juan Sebastian Hernández-Puentes
  • Alirio Rodrigo Bastidas-Goyes
  • Eduardo Tuta-Quintero
  • Diana Díaz-Quijano
  • Nicole Méndez Peñalosa
  • Nayah Zuleta Sanchez
  • María Herran Perez
  • Juan Rodríguez Sánchez
  • Valentina Ortiz Marquez
  • Ana Colmenares Leal
  • Juanita Zuleta Montañez
  • Laura Riveros Pedraza
  • Laura Sarmiento Cardozo
  • María Piñeros Clavijo
  • Maria Vasquez Bazurto
  • Isabella Lenhardt Guaqueta

Abstract

Background: Community-acquired pneumonia (CAP) represents a significant clinical challenge, particularly in patients with comorbidities, such as dementia, which increases the risk of mortality and hospitalization. Despite its relevance, dementia has not been considered a CAP severity assessment tool. Furthermore, there is limited information on this topic in Latin America. Therefore, this study aimed to analyze 30-day survival in patients with CAP and dementia in Colombia with the objective of identifying the impact of dementia on clinical outcomes and understanding this phenomenon in the region. Methods: A multicenter retrospective cohort study with survival analysis was conducted on patients with CAP admitted to two tertiary care institutions in Colombia between January 2010 and December 2020. Results: The study included 3,374 subjects: 354 (10.5%) with dementia and 3,020 (89.5%) without dementia. The mean age was 65.5 years, higher in the dementia group (82.5 vs. 63.5 years, p

Suggested Citation

  • Juan Sebastian Hernández-Puentes & Alirio Rodrigo Bastidas-Goyes & Eduardo Tuta-Quintero & Diana Díaz-Quijano & Nicole Méndez Peñalosa & Nayah Zuleta Sanchez & María Herran Perez & Juan Rodríguez Sánc, 2025. "Dementia as a risk factor for 30-day mortality in community-acquired pneumonia in Colombia (CAP): A survival study," PLOS ONE, Public Library of Science, vol. 20(10), pages 1-10, October.
    • Handle: RePEc:plo:pone00:0332713
    DOI: 10.1371/journal.pone.0332713
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