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Effect of exercise intensity on redox biomarkers in healthy adults: A systematic review and meta-analysis of randomized clinical trials

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  • Flor Isela Torres-Rojo
  • Liliana Aracely Enríquez-del Castillo
  • Susana Aidée González-Chávez
  • Luis Alberto Flores-Olivares
  • Estefanía Quintana-Mendias
  • Claudia Esther Carrasco-Legleu

Abstract

Purpose: This meta-analysis aimed to establish the effect of vigorous and non-vigorous exercise interventions on biomarkers of redox status in healthy adults. Materials and methods: Based on the PRISMA guidelines, we searched the following databases: Scopus, Web of Science, PubMed, Springer, Science Direct, Cochrane Library, Dialnet, Redalyc, and Lilacs for randomized controlled clinical trials investigating the effect of non-vigorous and vigorous chronic exercise in healthy adults, with the evaluation of antioxidants. The quality of evidence and risk of biases were assessed using the PEDro scale and version 2 of the Cochrane tool for risk of bias assessment in randomized trials (RoB2). Results: Seven randomized clinical trials evaluating nine training protocols were included (n=267). Individual evaluations demonstrated an increase in antioxidant capacity (I2=0%, Z=4.56, p

Suggested Citation

  • Flor Isela Torres-Rojo & Liliana Aracely Enríquez-del Castillo & Susana Aidée González-Chávez & Luis Alberto Flores-Olivares & Estefanía Quintana-Mendias & Claudia Esther Carrasco-Legleu, 2025. "Effect of exercise intensity on redox biomarkers in healthy adults: A systematic review and meta-analysis of randomized clinical trials," PLOS ONE, Public Library of Science, vol. 20(8), pages 1-15, August.
    • Handle: RePEc:plo:pone00:0330185
    DOI: 10.1371/journal.pone.0330185
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