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Health-Related Quality of Life measured with EQ-5D-5L among tuberculosis patients in Addis Ababa, Ethiopia: Institutional-based cross-sectional study

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  • Tenaw Baye Tarekegn
  • Getachew Alemkere
  • Eskinder Eshetu Ali

Abstract

Background: Tuberculosis (TB) substantially compromises health-related quality of life (HRQoL), yet limited studies have assessed its impact on Ethiopian patients using the EQ-5D instrument. This study evaluates HRQoL, estimates health state utility values, and identifies associated factors among TB patients in Ethiopia. Methods: A cross-sectional study was conducted across 20 public health centers in Addis Ababa, Ethiopia, involving 672 TB patients selected via proportional allocation. HRQoL was measured using the EuroQol five-dimension five-level (EQ-5D-5L) tool. Predictors of utility scores were analyzed using the Kruskal-Wallis test and Tobit censored regression models. Results: Anxiety/depression was the most frequently affected dimension (55.4% of participants). The mean EQ-5D-5L utility score was 0.91 (SD ± 0.14), and the mean EQ-VAS score was 80.6 (SD ± 15.6). Older age (55–64 years: β = −0.067, p

Suggested Citation

  • Tenaw Baye Tarekegn & Getachew Alemkere & Eskinder Eshetu Ali, 2025. "Health-Related Quality of Life measured with EQ-5D-5L among tuberculosis patients in Addis Ababa, Ethiopia: Institutional-based cross-sectional study," PLOS ONE, Public Library of Science, vol. 20(6), pages 1-15, June.
    • Handle: RePEc:plo:pone00:0326033
    DOI: 10.1371/journal.pone.0326033
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