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Unlocking the power of reticulocyte analysis: Advancing care for patients with abnormal haemoglobin variants at Eastern Regional Hospital, Koforidua

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  • Richard Vikpebah Duneeh
  • Israel Bedzina
  • Melody Yaaba Korkor Johnson
  • Francis Agyei Amponsah
  • Wina Ivy Ofori Boadu
  • Kenneth Ablordey

Abstract

Reticulocytes are immature erythrocytes that have been released into the peripheral circulation after being extruded from the bone marrow. However, it has not been investigated whether these reticulocyte indicators are helpful in treating conditions linked to abnormal haemoglobin variants. In the current investigation, participants with abnormal haemoglobin variants were evaluated for the utility of reticulocyte parameters using a high-end haematology analyser. We conducted a prospective cross-sectional study among 217 participants with abnormal haemoglobin variants at the Eastern Regional Hospital, Koforidua. Statistical analyses were performed with IBM SPSS V.26.0 (Chicago, IL, USA) and R programming language version 4.2.3. A p-value of

Suggested Citation

  • Richard Vikpebah Duneeh & Israel Bedzina & Melody Yaaba Korkor Johnson & Francis Agyei Amponsah & Wina Ivy Ofori Boadu & Kenneth Ablordey, 2025. "Unlocking the power of reticulocyte analysis: Advancing care for patients with abnormal haemoglobin variants at Eastern Regional Hospital, Koforidua," PLOS ONE, Public Library of Science, vol. 20(5), pages 1-14, May.
  • Handle: RePEc:plo:pone00:0323056
    DOI: 10.1371/journal.pone.0323056
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