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Real-world evidence in gynecologic cancers presented at key oncology conferences in the United States: Distribution and factors related to high-tier acceptance

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Listed:
  • Elizabeth A Szamreta
  • Mansi Modi
  • Ramu Periyasamy
  • Bhavani Yamsani
  • Pattabhi Machiraju
  • Neetu Menghani
  • Matthew Monberg

Abstract

Purpose: To describe the distribution, trends, and characteristics of types of real-world evidence (RWE) abstracts presented at key oncology congresses. Methods: Data on gynecologic cancers (cervical, ovarian, endometrial, and multiple gynecologic/other) were extracted from the American Society of Clinical Oncology (ASCO) and the Society of Gynecologic Oncology (SGO) conference databases (2018–2020) to: a) identify the proportion of clinical trial (CT) versus RWE abstracts accepted; b) describe the distribution and tier of acceptance of RWE versus CTs; c) analyze the characteristics (authorship, data source, data type, study design, outcome[s], and presence of statistically significant results) associated with RWE acceptance. Results: Of 3163 abstracts screened, 2271 (77% RWE, 23% CTs) were included. RWE represented a higher proportion of work at SGO versus ASCO (70% vs 30%). Overall, more RWE studies versus CTs were accepted as posters (75% vs 60%), while fewer were accepted as oral presentations (4% vs 20%; p

Suggested Citation

  • Elizabeth A Szamreta & Mansi Modi & Ramu Periyasamy & Bhavani Yamsani & Pattabhi Machiraju & Neetu Menghani & Matthew Monberg, 2025. "Real-world evidence in gynecologic cancers presented at key oncology conferences in the United States: Distribution and factors related to high-tier acceptance," PLOS ONE, Public Library of Science, vol. 20(4), pages 1-15, April.
    • Handle: RePEc:plo:pone00:0321654
    DOI: 10.1371/journal.pone.0321654
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