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Prevalence of Hepatitis C viral infection in Ghana: A systematic review and meta-analysis protocol

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  • Peter Kwabena Fosu
  • Gill ten Hoor
  • Charles Ampong Adjei
  • Fidelis Atibila
  • Robert A C Ruiter

Abstract

BackgroundHepatitis C virus (HCV) infection remains a major public health concern for many countries. A recent survey report in Ghana revealed a national HCV prevalence rate of 4.6% in a population of 35 million but with notably higher regional variations ranging from 8.6 to 14.4%. Considering that Ghana is targeting micro-elimination of HCV as part of the STOP Hepatitis C project, it is prudent to estimate the current epidemiological burden of hepatitis C for evidence-based policymaking, public health research, and program direction. An initial search of the literature showed a previous review that spanned from 1995 to 2015. The gap of almost 10 years may not reflect the current burden of hepatitis C in Ghana, hence this review. A systematic literature search will be performed in the major electronic databases and search engines including PubMed, Embase, Web of Science, CINAHL, and African Journals Online (AJOL). There will be a search for articles reporting on the prevalence of hepatitis C in Ghana from 2016 to 2024 in these databases. The protocol is registered with PROSPERO (CRD42024592505).

Suggested Citation

  • Peter Kwabena Fosu & Gill ten Hoor & Charles Ampong Adjei & Fidelis Atibila & Robert A C Ruiter, 2025. "Prevalence of Hepatitis C viral infection in Ghana: A systematic review and meta-analysis protocol," PLOS ONE, Public Library of Science, vol. 20(4), pages 1-7, April.
    • Handle: RePEc:plo:pone00:0321483
    DOI: 10.1371/journal.pone.0321483
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