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Prevalence and associated factors of dyslipidemia among adults with coexisting chronic disease in Ethiopia: A systematic review and meta-analysis

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  • Tadesse Mekonen Zeleke
  • Fitsum Endale Liben
  • Tinsae Shemelise Tesfaye
  • Abiyu Legesse Munea
  • Fekede Asefa Kumsa

Abstract

Introduction: Dyslipidemia is a well-established, modifiable risk factor for cardiovascular disease. This study aimed to determine the pooled prevalence of dyslipidemia, its components, and associated factors among adult patients residing in Ethiopia. Method: A comprehensive search of articles was conducted using MEDLINE, Embase, African Journals Online, Google Scholar, and University repositories. The quality of the studies was evaluated using the Joanna Briggs Institute quality appraisal criteria. Dyslipidemia was defined based on the National Cholesterol Education Program Adult Treatment Panel III cut-off points. We pooled the effect sizes using a random-effects model in Stata (v.16). Subgroup and sensitivity analysis were also performed. Small study effect was assessed by Luis Furuya-Kanamori asymmetry index, Doi plot, funnel plot, and Egger’s tests. Results: Out of 640 initially identified articles, 104 underwent full-text review, and 62 met the inclusion criteria for the final analysis. The pooled prevalence of overall dyslipidemia was 64% (95% CI: 54–74%; I2 = 98.74; P

Suggested Citation

  • Tadesse Mekonen Zeleke & Fitsum Endale Liben & Tinsae Shemelise Tesfaye & Abiyu Legesse Munea & Fekede Asefa Kumsa, 2025. "Prevalence and associated factors of dyslipidemia among adults with coexisting chronic disease in Ethiopia: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 20(4), pages 1-23, April.
    • Handle: RePEc:plo:pone00:0320119
    DOI: 10.1371/journal.pone.0320119
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