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The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis

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  • Xinru Li
  • Xiaofeng Li
  • Lintong Tan
  • Hu Chen
  • Yuan Lai

Abstract

Purpose: To evaluate the corneal biomechanical properties of phacoemulsification in the treatment of cataract patients. Methods: Pertinent studies were searched in PubMed, EMBASE, Web of Science and clinicaltrials.gov., as of November 05, 2024. The reference lists of related published reviews were included as well. This meta-analysis was performed with Stata Software and Review Manager, we used mean difference (MD) to evaluate the statistical consequence, using I2 statistic to assess the heterogeneity. Subgroup analysis were performed under the occurrences of high heterogeneity. We used eleven items to describe the characteristics of included studies, publication bias was performed with Egger’s test. The quality assessment were evaluated with 3 items by Newcastle-Ottawa Scale (NOS) items. Results: Thirteen eligible studies were identified for data synthesis and assessment. According to the result of meta-analysis, the central corneal thickness(CCT) (MD = 10.50, 95% CI: [5.01, 15.98]; P

Suggested Citation

  • Xinru Li & Xiaofeng Li & Lintong Tan & Hu Chen & Yuan Lai, 2025. "The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 20(1), pages 1-18, January.
    • Handle: RePEc:plo:pone00:0317179
    DOI: 10.1371/journal.pone.0317179
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