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The association between subfoveal choroidal thickness and refractive error in Taiwanese children: A cross-sectional study

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  • Li-Ying Huang
  • Lu-Ting Yu
  • Ning-Yi Hsia
  • Yi-Ching Hsieh
  • Hui-Ju Lin

Abstract

Purpose: The aim was to analyze the association of subfoveal choroidal thickness (SFCT) with age, best-corrected visual acuity, refractive error, and axial length in Taiwan pediatric population. Methods: A total of 374 eyes in 187 children were enrolled in this retrospective cross-sectional comparative study, who underwent examinations of best-corrected visual acuity (BCVA), cycloplegic refraction, and axial length (AL). Subfoveal choroidal thickness was assessed utilizing spectral domain enhanced depth imaging optical coherence tomography (EDI-OCT), with measurements taken at the subfovea, defined as the distance from the retinal pigment epithelium to the chorioscleral border. Results: The mean age was 5.6 ± 1.9 years (range 2–16 years). The cycloplegic spherical equivalent refractive error was between + 7.25 and - 15.25 diopters (D) and cycloplegic sphere power was between + 8.25 and - 11.5 diopters (D). The mean SFCT was 299.0 ± 69.80 μm. The mean axial length was 22.87 ± 1.29 mm. In univariate analysis, SFCT had significant positive correlations with spherical equivalent (SE) and sphere power (p

Suggested Citation

  • Li-Ying Huang & Lu-Ting Yu & Ning-Yi Hsia & Yi-Ching Hsieh & Hui-Ju Lin, 2025. "The association between subfoveal choroidal thickness and refractive error in Taiwanese children: A cross-sectional study," PLOS ONE, Public Library of Science, vol. 20(5), pages 1-9, May.
    • Handle: RePEc:plo:pone00:0316306
    DOI: 10.1371/journal.pone.0316306
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