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Prevalence and factors associated with microvascular and macrovascular diabetes complications in adult Ugandans: A systematic review and meta-analysis

Author

Listed:
  • Davis Kibirige
  • Ronald Olum
  • William Turyamureeba
  • Bethan Morgan
  • Andrew Peter Kyazze
  • Yakobo Nsubuga
  • Jerom Okot
  • William Lumu
  • Felix Bongomin

Abstract

Introduction: The rising prevalence of diabetes in Uganda has led to a disproportionate increase in the burden of diabetes complications. We conducted a systematic review and meta-analysis to document the prevalence and factors associated with five chronic diabetes complications in adult Ugandans with diabetes. Methods: We searched Medline, EMBASE, CINAHL, Cochrane Library, and Africa Journal Online databases from 25th May 2024–29th May 2024. We included studies reporting information on the prevalence and factors associated with the five chronic diabetes complications. We conducted a random-effect meta-analysis to determine the pooled prevalence of each diabetes complication. Using narrative synthesis, we described the factors significantly associated with each diabetes complication. Results: A total of twenty studies reporting information on 11,400 participants were considered. The pooled mean (standard deviation) age of the participants was 54.8 (3.6) years. Conclusions: This study demonstrates a high prevalence of chronic diabetes complications in adult Ugandans with diabetes. Timely screening and optimal management of chronic diabetes complications should be encouraged in Uganda.

Suggested Citation

  • Davis Kibirige & Ronald Olum & William Turyamureeba & Bethan Morgan & Andrew Peter Kyazze & Yakobo Nsubuga & Jerom Okot & William Lumu & Felix Bongomin, 2026. "Prevalence and factors associated with microvascular and macrovascular diabetes complications in adult Ugandans: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 21(6), pages 1-20, June.
    • Handle: RePEc:plo:pone00:0312792
    DOI: 10.1371/journal.pone.0312792
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