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Pericapsular nerve group block reduces opioid use and pain after hip surgery: A systematic review and meta-analysis of randomized controlled trials

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  • Xianghong Hu
  • Dahao Chenyang
  • Bin Xu
  • Yangjun Lao
  • Hongfeng Sheng
  • Shuliang Zhang
  • Yuliang Huang

Abstract

Background: While the pericapsular nerve group (PENG) block has become increasingly popular for managing pain after hip surgery, its efficacy remains controversial. Methods: We systematically searched Pubmed, Web of Science, Embase, and the Cochrane Library for randomized controlled trials to assess current evidence about the efficacy of the PENG block. Patients who received PENG block were compared to those who received sham/no block in terms of opioid consumption and pain within 24h after surgery, time to first opioid requirement, functional recovery, risk of nausea and vomiting, and patient dissatisfaction. The quality of evidence was assessed using the "Grading of Recommendations Assessment, Development and Evaluation" (GRADE) system. Results: We meta-analyzed six trials involving 416 patients who received preoperative PENG block and 415 who received sham/no block. Patients did not receive any other type of multimodal analgesia. Within 24 h after hip surgery, PENG block significantly reduced postoperative opioid consumption (MD = -12.03, 95% CI: -21.47 to -2.59, P

Suggested Citation

  • Xianghong Hu & Dahao Chenyang & Bin Xu & Yangjun Lao & Hongfeng Sheng & Shuliang Zhang & Yuliang Huang, 2024. "Pericapsular nerve group block reduces opioid use and pain after hip surgery: A systematic review and meta-analysis of randomized controlled trials," PLOS ONE, Public Library of Science, vol. 19(11), pages 1-15, November.
    • Handle: RePEc:plo:pone00:0310008
    DOI: 10.1371/journal.pone.0310008
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