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Trends of primary liver cancer incidence and mortality in the United States: A population-based study over the last four decades

Author

Listed:
  • Saryia Adra
  • Yousef Alabrach
  • Anas Hashem
  • Amir Mahmoud
  • Amani Khalouf
  • Ahmed El-khapery
  • Ali Abdelhay
  • Mohamad Mansour
  • Batool Aldaher
  • Hiba Barqawi
  • Eman Abu-Gharbieh

Abstract

Background: Primary liver cancer is the third leading cause of cancer deaths worldwide and has one of the worst 5-year survival rates. This study examines US primary liver cancer incidence and incidence-based mortality trends over four decades. Research design and methods: The SEER-9 registry was used to study primary liver cancer cases from 1978 to 2018. The incidence and mortality rates were calculated based on gender, age, race, and stage of diagnosis. Joinpoint regression software was used to calculate the annual percent change. Results: The overall incidence rate of primary liver cancer from 1978 to 2018 increased by 2.71%/year (p

Suggested Citation

  • Saryia Adra & Yousef Alabrach & Anas Hashem & Amir Mahmoud & Amani Khalouf & Ahmed El-khapery & Ali Abdelhay & Mohamad Mansour & Batool Aldaher & Hiba Barqawi & Eman Abu-Gharbieh, 2024. "Trends of primary liver cancer incidence and mortality in the United States: A population-based study over the last four decades," PLOS ONE, Public Library of Science, vol. 19(9), pages 1-14, September.
    • Handle: RePEc:plo:pone00:0309465
    DOI: 10.1371/journal.pone.0309465
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