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The impact of biologic agents on cardiovascular risk factors in patients with rheumatoid arthritis: A meta analysis

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  • Xiaodong Jia
  • Zheming Yang
  • Jiayin Li
  • Zhu Mei
  • Lihui Jia
  • Chenghui Yan

Abstract

Objective: The purpose of the study is to evaluate the effects of biologic therapy on cardiovascular risk factors in rheumatoid arthritis patients to determine its clinical efficacy. Methods: Relevant literature was systematically searched in PubMed, Embase, and Cochrane Library databases. Meta-analysis was conducted using standardized mean differences (SMDs) and 95% confidence intervals (CIs) to evaluate cardiovascular risk factors and atherosclerosis. Heterogeneity, sensitivity analysis, and publication bias were assessed. Statistical significance was set at P

Suggested Citation

  • Xiaodong Jia & Zheming Yang & Jiayin Li & Zhu Mei & Lihui Jia & Chenghui Yan, 2024. "The impact of biologic agents on cardiovascular risk factors in patients with rheumatoid arthritis: A meta analysis," PLOS ONE, Public Library of Science, vol. 19(8), pages 1-17, August.
    • Handle: RePEc:plo:pone00:0306513
    DOI: 10.1371/journal.pone.0306513
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