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Evaluation of agreement between a noninvasive method for real-time measurement of critical blood values with a standard point-of-care device

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  • Rudi H Ettrich
  • Joshua Caballero
  • Prashant Sakharkar
  • Sultan Ahmed
  • Traci Hurlston
  • Jayesh Parmar
  • Subrata Deb

Abstract

The purpose of this work was to investigate the degree of agreement between two distinct approaches for measuring a set of blood values and to compare comfort levels reported by participants when utilizing these two disparate measurement methods. Radial arterial blood was collected for the comparator analysis using the Abbott i-STAT® POCT device. In contrast, the non-invasive proprietary DBC methodology is used to calculate sodium, potassium, chloride, ionized calcium, total carbon dioxide, pH, bicarbonate, and oxygen saturation using four input parameters (temperature, hemoglobin, pO2, and pCO2). Agreement between the measurement for a set of blood values obtained using i-STAT and DBC methodology was compared using intraclass correlation coefficients, Passing and Bablok regression analyses, and Bland Altman plots. A p-value of

Suggested Citation

  • Rudi H Ettrich & Joshua Caballero & Prashant Sakharkar & Sultan Ahmed & Traci Hurlston & Jayesh Parmar & Subrata Deb, 2024. "Evaluation of agreement between a noninvasive method for real-time measurement of critical blood values with a standard point-of-care device," PLOS ONE, Public Library of Science, vol. 19(6), pages 1-13, June.
    • Handle: RePEc:plo:pone00:0304706
    DOI: 10.1371/journal.pone.0304706
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