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CT abnormalities 3 and 12 months after hospitalization for COVID-19 and association with disease severity: A prospective cohort study

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  • Trond Mogens Aaløkken
  • Haseem Ashraf
  • Gunnar Einvik
  • Tøri Vigeland Lerum
  • Carin Meltzer
  • Jezabel Rivero Rodriguez
  • Ole Henning Skjønsberg
  • Knut Stavem

Abstract

Objectives: To investigate changes in chest CT between 3 and 12 months and associations with disease severity in patients hospitalized for COVID-19 during the first wave in 2020. Materials and methods: Longitudinal cohort study of patients hospitalized for COVID-19 in 2020. Chest CT was performed 3 and 12 months after admission. CT images were evaluated using a CT severity score (CSS) (0–12 scale) and recoded to an abbreviated version (0–3 scale). We analyzed determinants of the abbreviated CSS with multivariable mixed effects ordinal regression. Results: 242 patients completed CT at 3 months, and 124 (mean age 62.3±13.3, 78 men) also at 12 months. Between 3 and 12 months (n = 124) CSS (0–12 scale) for ground-glass opacities (GGO) decreased from median 3 (25th–75th percentile: 0–12) at 3 months to 0.5 (0–12) at 12 months (p

Suggested Citation

  • Trond Mogens Aaløkken & Haseem Ashraf & Gunnar Einvik & Tøri Vigeland Lerum & Carin Meltzer & Jezabel Rivero Rodriguez & Ole Henning Skjønsberg & Knut Stavem, 2024. "CT abnormalities 3 and 12 months after hospitalization for COVID-19 and association with disease severity: A prospective cohort study," PLOS ONE, Public Library of Science, vol. 19(5), pages 1-16, May.
  • Handle: RePEc:plo:pone00:0302896
    DOI: 10.1371/journal.pone.0302896
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