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Cost-effectiveness and cost-utility analyses of three different gargles in the treatment of chronic periodontitis

Author

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  • Xin Chen
  • Wenzhi Niu
  • Guangyu Hu
  • Changfeng Chen

Abstract

Objective: This study aimed to investigate the economics of three different gargles in the treatment of chronic periodontitis. Methods: A total of 108 patients with periodontitis received one of the following three gargles: xipayi, compound chlorhexidine, or Kangfuxin gargle. The basic information of the patients, the costs of the gargles, the periodontal indexes before and after treatment, and the scores of the 3-level version of the EuroQol Five Dimensions Questionnaire were collected. The cost-effectiveness and cost-utility of the various gargles were determined. Results: The cost-effectiveness ratios (CER) of the three groups after treatment were 1828.75, 1573.34, and 1876.92 RMB, respectively. The utility values before treatment were 0.92, 0.90, and 0.91, respectively, and the utility values after treatment were 0.98, 0.98, and 0.97, respectively. The cost-utility ratios (CURs) were 213.43, 195.61, and 301.53 RMB, respectively. Conclusions: For each increase in effective rate and quality-adjusted life years, the treatment cost of periodontitis patients was lower than the gross domestic product per capita of Jiangsu Province, indicating that the treatment cost is completely worth it. The CER and CUR results were the same, and the compound chlorhexidine group was the lowest, demonstrating that when the same therapeutic effect was achieved, it cost the least.

Suggested Citation

  • Xin Chen & Wenzhi Niu & Guangyu Hu & Changfeng Chen, 2024. "Cost-effectiveness and cost-utility analyses of three different gargles in the treatment of chronic periodontitis," PLOS ONE, Public Library of Science, vol. 19(5), pages 1-11, May.
    • Handle: RePEc:plo:pone00:0302592
    DOI: 10.1371/journal.pone.0302592
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