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Association between rosacea and helicobacter pylori infection: A meta-analysis

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  • Ying Gao
  • Xiao-jing Yang
  • Yun Zhu
  • Ming Yang
  • Fei Gu

Abstract

Background and objectives: The potential association between rosacea and a heightened prevalence of Helicobacter pylori (HP) infection has been previously suggested. However, existing studies offer inconsistent results. This systematic review and meta-analysis aimed to elucidate the relationship between rosacea and HP infection. Methods: We conducted comprehensive searches of PubMed, Embase, and Web of Science databases to identify relevant observational studies for our investigation. We utilized the random-effects model to aggregate the data to address the potential influence of heterogeneity among the studies on the outcome. Results: Our analysis incorporated twenty-five datasets from 23 case-control and cross-sectional studies, encompassing 51,054 rosacea patients and 4,709,074 controls without skin disease. The pooled results revealed a significantly higher prevalence of HP infection in individuals with rosacea compared to controls (odds ratio [OR]: 1.51, 95% confidence interval [CI]: 1.17–1.95, p

Suggested Citation

  • Ying Gao & Xiao-jing Yang & Yun Zhu & Ming Yang & Fei Gu, 2024. "Association between rosacea and helicobacter pylori infection: A meta-analysis," PLOS ONE, Public Library of Science, vol. 19(4), pages 1-13, April.
    • Handle: RePEc:plo:pone00:0301703
    DOI: 10.1371/journal.pone.0301703
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