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Prevalence and risk factors of early postoperative seizures in patients with glioma: A protocol for meta-analysis and systematic review

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  • Bo Sun
  • Wenpeng Lu
  • Wangyang Yu
  • Ye Tian
  • Peng Wang

Abstract

Introduction: Early postoperative seizures has been the most common clinical expression in gliomas; however, the incidence and risk factors for early postoperative seizures in gliomas are more controversial. This protocol describes a systematic review and meta-analysis to clarify the prevalence and risk factors of early postoperative seizures in patients with glioma. Methods and analysis: Searches will be conducted on CNKI, WanFang, VIP, PubMed, Embase, Cochrane Library databases and Web of Science for the period from database inception to December 31st, 2023. Case-control and cohort studies of the incidence and risk factors for early postoperative seizures in all gliomas will be included. The primary outcome will be incidence, risk factors. Newcastle-Ottawa Scale was used for quality evaluation. Review of article screening, extracting data and risk of bias assessment will be repeated by two independent reviewers. Result: This study will provide evidence for the risk factors and incidence of early postoperative seizures in patients with glioma. Conclusion: Our study will provide evidence for the prevention of early postoperative seizures in glioma patients. Trail registration: This protocol was registered in PROSPERO and registration number is CRD42023415658.

Suggested Citation

  • Bo Sun & Wenpeng Lu & Wangyang Yu & Ye Tian & Peng Wang, 2024. "Prevalence and risk factors of early postoperative seizures in patients with glioma: A protocol for meta-analysis and systematic review," PLOS ONE, Public Library of Science, vol. 19(4), pages 1-8, April.
    • Handle: RePEc:plo:pone00:0301443
    DOI: 10.1371/journal.pone.0301443
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