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Underwater versus conventional endoscopic mucosal resection for ≥10 mm sessile or flat colorectal polyps: A systematic review and meta-analysis

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  • Xue Wang
  • Yue Wang
  • Xueyan Cao
  • Chunmei Zhang
  • Lin Miao

Abstract

Background and aim: Underwater endoscopic mucosal resection (UEMR) has been an emerging substitute for conventional EMR (CEMR). This systematic review and meta-analysis aimed at comparing the efficiency and safety of the two techniques for removing ≥10 mm sessile or flat colorectal polyps. Methods: PubMed, Cochrane Library and Embase databases were searched up to February 2023 to identify eligible studies that compared the outcomes of UEMR and CEMR. This meta-analysis was conducted on the en bloc resection rate, R0 resection rate, complete resection rate, procedure time, adverse events rate and recurrence rate. Results: Nine studies involving 1,727 colorectal polyps were included: 881 were removed by UEMR, and 846 were removed by CEMR. UEMR was associated with a significant increase in en bloc resection rate [Odds ratio(OR) 1.69, 95% confidence interval(CI) 1.36–2.10, p

Suggested Citation

  • Xue Wang & Yue Wang & Xueyan Cao & Chunmei Zhang & Lin Miao, 2024. "Underwater versus conventional endoscopic mucosal resection for ≥10 mm sessile or flat colorectal polyps: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 19(3), pages 1-15, March.
  • Handle: RePEc:plo:pone00:0299931
    DOI: 10.1371/journal.pone.0299931
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