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Investigating the association between diabetes and carpal tunnel syndrome: A systematic review and meta-analysis approach

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  • Elaheh Sanjari
  • Hadi Raeisi Shahraki
  • Lusine G. Khachatryan
  • Abdollah Mohammadian-Hafshejani

Abstract

Introduction: In recent years, several studies have reported on the relationship between diabetes and carpal tunnel syndrome (CTS). However, due to their contradictory results, a systematic review and meta-analysis were conducted to investigate this subject. Methods: This study is a systematic review and meta-analysis of studies published in ISI Web of Science, Scopus, PubMed, Cochrane, Google Scholar, and Embase databases. Heterogeneity in the studies included in the meta-analysis was evaluated using statistical tests such as the Chi-square test, I2, and forest plots. Publication bias was assessed using Begg’s and Egger’s tests. Results: This investigation analyzed data from 42 studies conducted between 1985 and 2022, with a total of 3,377,816 participants. The meta-analysis demonstrated that the odds ratio (OR) of CTS in participants with a history of diabetes compared to those without was 1.90 (95% CI: 1.64–2.21; P-value

Suggested Citation

  • Elaheh Sanjari & Hadi Raeisi Shahraki & Lusine G. Khachatryan & Abdollah Mohammadian-Hafshejani, 2024. "Investigating the association between diabetes and carpal tunnel syndrome: A systematic review and meta-analysis approach," PLOS ONE, Public Library of Science, vol. 19(4), pages 1-17, April.
    • Handle: RePEc:plo:pone00:0299442
    DOI: 10.1371/journal.pone.0299442
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