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Internal limiting membrane peeling in rhegmatogenous retinal detachment: A meta-analysis

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  • Guohai Chen
  • Radouil Tzekov
  • Yan Fang
  • Yuhua Tong
  • Wensheng Li

Abstract

Purpose: To determine whether pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling for rhegmatogenous retinal detachment (RRD) could get better functional and anatomical outcomes. Methods: A comprehensive literature search was performed to find relevant studies. A meta-analysis was conducted by comparing the weighted mean differences (WMD) in the mean change of best corrected visual acuity (BCVA) from baseline and calculating the odd ratios (OR) for rates of epiretinal membrane (ERM) formation and recurrence of retinal detachment (RD). Results: Fourteen studies were selected, including 2259 eyes (825 eyes in the ILM peeling group and 1434 eyes in the non-ILM peeling group). There was no significant difference in terms of mean change in BCVA from baseline and the rate of RD recurrence (WMD = 0.02, 95% CI, -0.20 to 0.24, P = 0.86, and OR = 0.55, 95% CI, 0.24 to 1.26, P = 0.16), but ILM peeling was associated with a significantly lower frequency of postoperative ERM formation (OR = 0.13, 95% CI, 0.06 to 0.26, P

Suggested Citation

  • Guohai Chen & Radouil Tzekov & Yan Fang & Yuhua Tong & Wensheng Li, 2024. "Internal limiting membrane peeling in rhegmatogenous retinal detachment: A meta-analysis," PLOS ONE, Public Library of Science, vol. 19(3), pages 1-14, March.
    • Handle: RePEc:plo:pone00:0297230
    DOI: 10.1371/journal.pone.0297230
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