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Effects of acupuncture treatment for myasthenia gravis: A systematic review and meta-analysis

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  • Hua Xue
  • Li Zeng
  • Hongxian He
  • Dongxun Xu
  • Kaixin Ren

Abstract

Background: Randomized controlled trials (RCTs) of acupuncture for myasthenia gravis (MG) were searched and the efficacy of acupuncture in the treatment of MG was evaluated by meta-analysis. Methods: We searched for RCTs in six main electronic databases, and collected RCTs of acupuncture treatment for MG from database creation to 28 February 2023. The main outcome was the effective rate and the secondary outcome was the Traditional Chinese Medicine (TCM) relative clinical score, absolute clinical score (ACS) of MG, Quantitive myasthenia gravis score (QMG), quality of life, and adverse events. Odds ratios (ORs) and weighted mean differences (WMD) and 95% confidence intervals (CI) were used to assess pooled effect estimates using Review Manager software. Results: A total of 14 RCTs were included. Meta-analysis showed that the effective rate in the acupuncture group was significantly improved compared with conventional Western medicine alone [OR = 4.28, 95% CI (2.95, 6, 22), P

Suggested Citation

  • Hua Xue & Li Zeng & Hongxian He & Dongxun Xu & Kaixin Ren, 2024. "Effects of acupuncture treatment for myasthenia gravis: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 19(1), pages 1-15, January.
    • Handle: RePEc:plo:pone00:0291685
    DOI: 10.1371/journal.pone.0291685
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