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Large regional variation in cardiac closure procedures to prevent ischemic stroke in Switzerland a population-based small area analysis

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  • Nina Stoller
  • Maria M Wertli
  • Alan G Haynes
  • Arnaud Chiolero
  • Nicolas Rodondi
  • Radoslaw Panczak
  • Drahomir Aujesky

Abstract

Background: Percutaneous closure of a patent foramen ovale (PFO) or the left atrial appendage (LAA) are controversial procedures to prevent stroke but often used in clinical practice. We assessed the regional variation of these interventions and explored potential determinants of such a variation. Methods: We conducted a population-based analysis using patient discharge data from all Swiss hospitals from 2013–2018. We derived hospital service areas (HSAs) using patient flows for PFO and LAA closure. We calculated age-standardized mean procedure rates and variation indices (extremal quotient [EQ] and systematic component of variation [SCV]). SCV values >5.4 indicate a high and >10 a very high variation. Because the evidence on the efficacy of PFO closure may differ in patients aged

Suggested Citation

  • Nina Stoller & Maria M Wertli & Alan G Haynes & Arnaud Chiolero & Nicolas Rodondi & Radoslaw Panczak & Drahomir Aujesky, 2024. "Large regional variation in cardiac closure procedures to prevent ischemic stroke in Switzerland a population-based small area analysis," PLOS ONE, Public Library of Science, vol. 19(1), pages 1-17, January.
    • Handle: RePEc:plo:pone00:0291299
    DOI: 10.1371/journal.pone.0291299
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