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Defining an optimal cut-off point for reticulocyte hemoglobin as a marker for iron deficiency anemia: An ROC analysis

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  • Marah Alzu’bi
  • Hisham Bawa’neh
  • Alaa Alshorman
  • Jawad Alrawabdeh
  • Nada Odeh
  • Yazan Hamadneh
  • Mai AlAdwan
  • Mahmoud Odeh
  • Abdalla Awidi

Abstract

Reticulocyte hemoglobin (CHr) is a measure of the amount of hemoglobin in reticulocytes and a marker of cell hemoglobinization. In this study, we aimed to find the optimal cut-off point for reticulocyte hemoglobin to diagnose iron deficiency anemia using multiple methods. A total of 309 patients were included. The median age at diagnosis was 54 years. Most were females (71.2%). 68% had iron deficiency anemia. Patients with IDA had significantly lower levels of CHr compared to those who had non-IDA (p

Suggested Citation

  • Marah Alzu’bi & Hisham Bawa’neh & Alaa Alshorman & Jawad Alrawabdeh & Nada Odeh & Yazan Hamadneh & Mai AlAdwan & Mahmoud Odeh & Abdalla Awidi, 2023. "Defining an optimal cut-off point for reticulocyte hemoglobin as a marker for iron deficiency anemia: An ROC analysis," PLOS ONE, Public Library of Science, vol. 18(7), pages 1-7, July.
    • Handle: RePEc:plo:pone00:0288505
    DOI: 10.1371/journal.pone.0288505
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