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COVID-19 symptom load as a risk factor for chronic pain: A national cross-sectional study

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  • Jamie L Romeiser
  • Christopher P Morley
  • Sunitha M Singh

Abstract

Introduction: Emerging evidence suggests that a COVID-19 infection with a high initial severity may be associated with development of long-COVID conditions such as chronic pain. At the population level, it is unknown if severity of a COVID-19 infection might be a new risk factor for chronic pain above and beyond the traditional slate of pre-established risk factors. The purpose of this study is to examine whether COVID-19 severity of infection may be a new risk factor for chronic pain. Methods: Using data from the 2021 National Health Interview Survey (n = 15,335), this study examined the adjusted odds of experiencing high frequency levels of pain in the past 3 months for those who reported no/mild symptoms from a COVID-19 infection, and those reporting moderate/severe symptoms from COVID-19, compared to those never infected. A 1:1:1 propensity score matched analysis was also performed to examine the odds of pain. Results: Prevalence of pain was higher in the moderate/severe symptom group compared to the no infection group (25.48% vs 19.44%, p

Suggested Citation

  • Jamie L Romeiser & Christopher P Morley & Sunitha M Singh, 2023. "COVID-19 symptom load as a risk factor for chronic pain: A national cross-sectional study," PLOS ONE, Public Library of Science, vol. 18(6), pages 1-13, June.
    • Handle: RePEc:plo:pone00:0287554
    DOI: 10.1371/journal.pone.0287554
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