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Early versus late amniotomy during induction of labor using oxytocin: A randomized controlled trial

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  • Ahmed Halouani
  • Yassine Masmoudi
  • Rym Hamdaoui
  • Aymen Hammami
  • Amel Triki
  • Anissa Ben Amor

Abstract

Objective: To assess the effect of early amniotomy on labor duration, maternal and neonatal outcomes during induction of labor (IOL). Methods: This was a randomized controlled trial, conducted over a period of eight months at a monocentric site. Singleton pregnancies in nulliparous and parous patients with cephalic presentation and Bishop score ≥ 6 were enrolled in the study. One hundred participants were randomized into two groups: early amniotomy (initiating IOL with amniotomy followed by oxytocin) versus late amniotomy (initiating IOL with oxytocin followed by amniotomy 4 hours later). The primary endpoint was the time to active phase (cervical dilation ≥ 5 cm) during IOL. Secondary outcomes were time to vaginal delivery, mode of delivery, and maternal and fetal outcomes. Results: Early amniotomy reduced time to active phase by 2 hours and 46 minutes compared to the late amniotomy group (3 h 42 min vs. 6 h 28 min; p

Suggested Citation

  • Ahmed Halouani & Yassine Masmoudi & Rym Hamdaoui & Aymen Hammami & Amel Triki & Anissa Ben Amor, 2023. "Early versus late amniotomy during induction of labor using oxytocin: A randomized controlled trial," PLOS ONE, Public Library of Science, vol. 18(5), pages 1-11, May.
    • Handle: RePEc:plo:pone00:0286037
    DOI: 10.1371/journal.pone.0286037
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