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Comparison of femtosecond laser-assisted cataract surgery and conventional phacoemulsification on corneal impact: A meta-analysis and systematic review

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  • Hanle Wang
  • Xinyi Chen
  • Jingjie Xu
  • Ke Yao

Abstract

This meta-analysis aims to compare corneal injuries and function after femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS). A comprehensive literature search of PubMed, EMBASE, and the Cochrane Controlled Trials Register was conducted to identify randomized controlled trials (RCT) and high-quality prospective comparative cohort studies comparing FLACS with CPS. Endothelial cell loss percentage (ECL%), central corneal thickness (CCT), endothelial cell density (ECD), endothelial cell loss (ECL), percentage of the hexagonal cell (6A), and coefficient of variance (CoV) were used as an indicator of corneal injury and function. Totally 42 trials (23 RCTs and 19 prospective cohort studies), including 3916 eyes, underwent FLACS, and a total of 3736 eyes underwent CPS. ECL% is significantly lower in the FLACS group at 1–3 days (P = 0.005), 1 week (P = 0.004), 1 month (P

Suggested Citation

  • Hanle Wang & Xinyi Chen & Jingjie Xu & Ke Yao, 2023. "Comparison of femtosecond laser-assisted cataract surgery and conventional phacoemulsification on corneal impact: A meta-analysis and systematic review," PLOS ONE, Public Library of Science, vol. 18(4), pages 1-19, April.
    • Handle: RePEc:plo:pone00:0284181
    DOI: 10.1371/journal.pone.0284181
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    1. Xinyi Chen & Kailin Chen & Jiliang He & Ke Yao, 2016. "Comparing the Curative Effects between Femtosecond Laser-Assisted Cataract Surgery and Conventional Phacoemulsification Surgery: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(3), pages 1-14, March.
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