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Referral pattern to nephrologist and prognosis in diabetic kidney disease patients: Single center retrospective cohort study

Author

Listed:
  • Yukimasa Iwata
  • Terumasa Hayashi
  • Hiroki Okushima
  • Ryuta Uwatoko
  • Taisuke Takatsuka
  • Daisuke Yoshimura
  • Tomohiro Kawamura
  • Rei Iio
  • Yoshiyasu Ueda
  • Tatsuya Shoji
  • Yoshitaka Isaka

Abstract

Background: Management of diabetic kidney disease (DKD) to prevent end-stage kidney disease (ESKD) has become a major challenge for health care professionals. This study aims to investigate the characteristics of patients with DKD when they are first referred to a nephrologist and the subsequent prognoses. Methods: A total of 307 patients who were referred to our department from October 2010 to September 2014 at Osaka General Medical Center were analyzed. Independent risk factors associated with renal replacement therapy (RRT) and cardiovascular composite events (CVE) following their nephrology referral were later identified using Cox proportional hazards analysis. Results: Of 307 patients, 26 (8.5%), 67 (21.8%), 134 (43.6%), and 80 (26.1%) patients were categorized as having chronic kidney disease (CKD) stages 3a, 3b, 4, and 5, respectively. The median estimated glomerular filtration rate (eGFR) and urinary protein levels were 22.3 mL/min/1.73 m2 and 2.83 g/gCr, respectively, at the time of the nephrology referral. During the follow-up period (median, 30 months), 121 patients required RRT, and more than half of the patients with CKD stages 5 and 4 reached ESKD within 60 months following their nephrology referral; 30% and

Suggested Citation

  • Yukimasa Iwata & Terumasa Hayashi & Hiroki Okushima & Ryuta Uwatoko & Taisuke Takatsuka & Daisuke Yoshimura & Tomohiro Kawamura & Rei Iio & Yoshiyasu Ueda & Tatsuya Shoji & Yoshitaka Isaka, 2023. "Referral pattern to nephrologist and prognosis in diabetic kidney disease patients: Single center retrospective cohort study," PLOS ONE, Public Library of Science, vol. 18(2), pages 1-13, February.
    • Handle: RePEc:plo:pone00:0282163
    DOI: 10.1371/journal.pone.0282163
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    References listed on IDEAS

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    1. Rupert W Major & Mark R I Cheng & Robert A Grant & Saran Shantikumar & Gang Xu & Issaam Oozeerally & Nigel J Brunskill & Laura J Gray, 2018. "Cardiovascular disease risk factors in chronic kidney disease: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 13(3), pages 1-18, March.
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