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Association between vitamin D concentration and delirium in hospitalized patients: A meta-analysis

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  • Ningning Fu
  • Mengrong Miao
  • Ningning Li
  • Shuang Zeng
  • Ruilou Zhu
  • Jiaqiang Zhang

Abstract

Background: Now the occurrence of delirium is more concerning to clinicians and psychiatrists. It has been reported that vitamin D deficiency may be a relevant factor in the development of delirium in hospitalized patients. Study objective: To investigate the association between vitamin D concentration and delirium in hospitalized patients. Design: Meta-analysis. Methods: A systematic literature search was conducted using PubMed, EMBASE, and the Cochrane Library. The primary outcome was the occurrence of delirium in the inpatient setting. Odds ratios (OR) were calculated with random or fixed effects models. Results: In this article, we define the normal range of vitamin D concentrations as greater than 75 nmol / L, 50–75 nmol / L as vitamin D insufficiency, 25–50 nmol / L as vitamin D deficiency, and less than 25 nmol / L as vitamin D severe deficiency. The Results showed that severe vitamin D deficiency (OR: 1.98 [1.41–2.79], P

Suggested Citation

  • Ningning Fu & Mengrong Miao & Ningning Li & Shuang Zeng & Ruilou Zhu & Jiaqiang Zhang, 2023. "Association between vitamin D concentration and delirium in hospitalized patients: A meta-analysis," PLOS ONE, Public Library of Science, vol. 18(2), pages 1-16, February.
    • Handle: RePEc:plo:pone00:0281313
    DOI: 10.1371/journal.pone.0281313
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